Pathology 3500 Lecture Notes - Lecture 7: Serous Fluid, Vascular Disease, Macrophage

• School: Western University
• Department: Pathology
• Course: Pathology 3500
• Professor: shepherd

Document Summary

Lecture 7 - classifying inflammation and wound healing. Classifying inflammation: by duration, by predominant type of exudate, by location and special forms. Agents causing inflammation: trauma, metabolic injuries, anoxia, physical agents. Exudation: outpouring of fluids, proteins and cells from vessels into interstitium or body cavities, exudate is extravascular fluid rich in proteins and cells with a specific gravity of >1. 020. It implies significant alteration in the normal permeability of small blood vessels in the area of injury: comes from vascular tissue, goes into interstitial space (space surrounding tissue, high in protein concentration. Transudation: outpouring of fluid with little protein (albumin) with a specific gravity of <1. 012, transudate is ultrafiltrate of plasma and it is usually due to hydrostatic imbalance, permeability is normal, not a lot of protein and cells. Fluid is pushed out of vascular compartment therefore the cells and proteins cant fit and are kept back. Long flight and feet get swollen this is edema.