Pathology 2420A Lecture Notes - Lecture 2: Cytoskeleton, Protein Isoform, Coagulative Necrosis

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Adaption when cells are exposed to an adverse stimulus. Anoxia absence or almost absence of oxygen from inspired gases, arterial blood, or. Hypoxia decrease of oxygen in inspired gases, arterial blood, tissues. Apoptosis programmed cell death (most often during development, occurs after. Atrophy decrease in tissue mass due to shrinkage of cells. Hypertrophy increase in size of existing cells. Irreversible cell injury cell has no time to mount an adaptive response (most often. Reversible cell injury when stimulus is removed, the cell goes back to normal. Dysplasia alteration to size, shape, organization of the cells. Metaplasia substitute of one type of cell for another. Fatty change accumulation of fat in cells (in liver cells = alcoholism) Hemosiderin insoluble form of tissue storage iron. Hydropic swelling increase in cell volume due to impairment of ion regulation. Lipofuscin brownish pigment from lipids and cell mb over time. Ischemia local decrease in blood supply due to mechanical obstruction (most often.

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