Pathology 2420A Lecture 12: Pathology Final Exam Review – Module 12

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Pathology final exam review module 12, diseases of the cns. Specify the conditions for regeneration of damaged neuronal processes. Sectioning the axon of a neuron has different consequences in the cns and the pns. In both cases, the distal segment degenerates, since it cannot survive without the continuous transport of substances manufactured in the soma. In the pns, the proximal stump gives rise to sprouts that are able to grow along the pre-existing structures (schwann cells) and re-establish function. The only requirement is the apposition of the proximal and distal stump. In contrast, axonal regeneration regularly fails in the. Coup = site of impact, contre-coup = at base of the brain, caused by movement over the rough surface of the base of the skull, often more prominent on the side opposite the impact. Their incidence has decreased in recent years, with better control of hypertension in the greater population. Clinical symptoms include fever, stiffened neck, clouding of consciousness.

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