Pathology 2420A Lecture Notes - Lecture 11: Anal Canal, Exudate, Enema
10 Nov 2016
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You should: review the clinical symptoms associated with appendicitis, be familiar with its pathogenesis, general descriptive pathology and the role of inflammation (review your inflammation notes re: the cell types involved and correlation of clinical signs with pathology). A 13 year old female complained of peri-umbilical pain. One day later the pain intensified and was more prominent at palpation of the right lower quadrant. Abdominal palpation revealed tenderness and guarding with rebound tenderness. She had not had a bowel movement for 48 hours. Her white cell differential count showed 95% polymorphonuclear neutrophils. This case illustrates many of the features of acute appendicitis. Clinically, appendicitis presents with epigastric or periumbilical cramping pain. The pain shifts to the lower right quadrant where rebound tenderness is the rule. Acute appendicitis may occur at any age, but is most common between the ages of 10 to 25 years. The appendix grossly is congested and often covered with a fibrous or purulent exudate.
