Pathology 2420A Lecture Notes - Lecture 5: Benign Prostatic Hyperplasia, Squamous Cell Carcinoma, Prostate Cancer

• School: Western University
• Department: Pathology
• Course: Pathology 2420A
• Professor: Candace Gibson

Document Summary

This module will provide an understanding of the pathogenesis and pathology of neoplasia and its clinical significance. Anaplasia - complete lack of differentiation; cell has reverted back to its nondifferentiated or primitve form - variable cell and nuclear size and shape, increased chromatin, increased and atypical mitosis. Benign tumour - a tumour that does not invade or spread. Cancer - the general term used for malignant neoplasms. Dysplasia - abnormal tissue development, may see changes in nucleus (irregular nucleus - increased size or change in shape, increased number of nucleoli, increased amount of chromatin) or cytoplasm; may be reversible. Malignant tumour - defined by the ability to invade local tissues and spread to distant sites (metastasis). Metastasis - the ability of a cancer to spread to other parts of the body through the blood or lymph circulation and establish and grow new tumours; Metastases refers to the secondary tumours that are implanted at the distant site.