Pathology 3240A Lecture Notes - Lecture 24: Preterm Birth, Umbilical Hernia, Polydactyly
10 Nov 2015
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Perinatal infections: refers to infections around the time of birth and may be acquired in two ways, transcervically (ascending, transplacentally (hematologically) Transplacentally: a perinatal infection carried through blood or placental barrier, only certain infections can cross through the blood (hematological) or cross the placenta (viruses, parasites, some bacteria, torch: acronym for things which can cause trasnplacental infections including. Toxoplasma, rubella, cmv, herpes, and others (e. g. , t. pallidum: they can cause anything from anemia (blood), heart issue, bone marrow, gever, encephalitis, chorioretinitis, hepatosplenomegaly, pneumonia, myocarditis, anemia. Encephalitis = brain, anemia = blood, chorioretinitis =eyes, heptosplenomegaly is liver/spleen, pneumonia is lungs: ex. Toxoplasmosis is very common parasite found in cat feces which can cross the placenta, to cause still birth, ophthalmologic and neurologic problems (eyes and cns: the baby lacks an immune system. Mental retardation, prominent occiput, micrognathi, overlapping fingers, congenital heart defects. Intrauterine hypoxia from nuchal cord: cord wraps around the newborns neck, prematurity.
