Pathology 3240A Lecture Notes - Lecture 15: Selective Immunoglobulin A Deficiency, Chronic Granulomatous Disease, Vitamin D Deficiency
Document Summary
Infectious diseases may be: minor nuisance, dramatically affect our history and society, smallpox native americans, black death (plague) europe. Increased incidence of antimicrobial resistance: re-emergence of disease causing organisms that had been on the decline, organisms appearing from other parts of the world, ex. West nile disease: new pathogens identified in the last 30 years, ebola virus, hanta virus, e. coli o157, legionella pneumophilia, hiv, hep c, helicobacter pylori, sars. Objectives: concept of infectious disease, examples of some infectious diseases. Infectious disease occurs when a pathogenic organism causes signs and symptoms of inflammation or organ dysfunction. For an organism to cause disease, it must fulfill koch"s postulates: found in lesions of disease, organism can be isolated in vitro, can be transmitted to animals, can be recovered from animal. Determining that a specific disease is due to a specific infectious agent based on koch"s postulates allows us to: diagnosis, treatment, epidemiology source, transmission, prevention.