Nursing 4400A/B Lecture 9: Week 9 Reading Notes

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Cigarette smoke contributes to cad in the following 3 ways: By increasing carbon monoxide in the blood (attached to hempglobin) and thus decreasing the amount of o2 provided to the heart. The nicotinic acid in cigarettes also increases heart rate, bp, and constricts the coronary arteries. Causes a detrimental vascular response and thus increases platelet formation and thus the risk of thrombus formation. Ultimately a person with an increased risk for heart disease should be encouraged to stop smoking tobacco decreases the risk by 30-50% Bp exceeding 140/90 on a regular basis. This leads to stiffness of the vessels, leading to vessel injury, an inflammatory response which causes growing hormones to be released which may then lead to atherosclerosis. May also cause hypertrophy of the heart if the walls thicken which can lead to heart failure. Hyperglycemia causes dyslipidemia, increased platelet aggregation, and altered red blood cell function. Should be treated with metformin and insulin to decrease risk.

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