Microbiology and Immunology 3820A Lecture 10: 3820 - Week 10 Lecture
8 Apr 2018
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Document Summary
Mycobacteria classification: tubercle bacilli complex, mott (mycobacteria other than tubercle bacilli, non tuberculosis mycobacteria, mycobacterium leprae (causal agent of leprosy, tuberculosis complex, mycobacterium tuberculosis, mycobacterium bovis, mycobacterium africanum, mycobacterium canettii, mycobacterium microti, mycobacterium caprae. Tuberculosis: (cid:1005)/(cid:1007) of the (cid:449)orld"s populatio(cid:374) infected, ~30 million active cases. If the sputum stains negative for afb patient is noninfectious. Incidence of tb is low in north america except in first nations, inuit, refugees, aids and the homeless. Tuberculosis: most pulmonary tb in adults is in the apical areas, which have seeded via the hematogenous route from an often undetected primary focus in the lower lung. 2: extrapulmonary tb (15%) is acquired via hematogenous seeding and is almost noncontagious, no body tissue is immune to infection, except tooth enamel, reactivation tb may occur if the recovered patient becomes immunocompromised. Mantoux test: intradermal injection of 5 tuberculin units of ppd. Induration (not erythema) is measured in mm 48-72 hours later.
