Microbiology and Immunology 2500A/B Lecture Notes - Lecture 15: Mycobacterium Tuberculosis, Mycobacterium Leprae, Mycobacterium Bovis
7 Jun 2019
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Tuberculosis and leprosy lecture 15 feb. 11th, 2019: causative agent of tuberculosis in humans, humans are the only known reservoir, often called "tb" for tubercle bacilli (lesions in lungs) M. bovis: causes tuberculosis in cows, rarely in humans, humans can be infected by the consumption of unpasteurized milk leading to extrapulmonary tuberculosis. M. avium: can cause a tuberculosis-like illness in humans, particularly in aids patients (immunocompromised, pathogen of birds. M. leprae: causative agent of leprosy in humans. 1/3 of the world"s total population (> 2 billion people) are infected with tb: extraordinarily fit. 1/10 infected with tb will develop active tb in their lifetime: most people never actually progress to disease. Tb is contagious and spread through air. If not treated, each person with active tb can infect 10-15 people a year on average. Tb is leading killer among people living with hiv.
