Microbiology and Immunology 2500A/B Lecture Notes - Lecture 23: Ebola Virus, Orthomyxoviridae, Hepatitis B Virus

• School: Western University
• Department: Microbiology and Immunology
• Course: Microbiology and Immunology 2500A/B
• Professor: Dimitrios J Dikeakos, John Mc Cormick, Kelly Lynn Summers

Document Summary

Understand the different pieces that make a virus. In order for viruses to survive they must: Use this particle to transfer their genome from host to host. Genome contains information to initiate and complete the viral infectious cycle. Genome establish themselves in host ensuring long term survival. Protamer unit forming a capsule or nucleocapsid. Capsid protects the viral genome: able to transmit and create viral infectious cycle, need units. One triangle = smallest unit = single polypeptide. Triangle units tend to form groups in different numbers: one triangle forms a pair with another triangle. Patterns often repeated in a very efficient and specific manner for the principle of viral economy: triangle pair bonding is repeated all around the box to protect the viral genome. Nucleocapsid situation where the capsid also contains the genome. Viruses that have these types of nucleocapsids often have a secondary shell around it . The virion must be both stable & unstable.