Kinesiology 3371A/B Lecture Notes - Lecture 6: Vascular Endothelial Growth Factor, Endoplasmic Reticulum, Neurotrophic Factors
4 Jan 2020
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Document Summary
Dementia spectrum > cognitive decline > brain function > biomarkers (may be why brain function is changing) Exercise improves cognition: directly: increase cerebral blood ow, increased in ammatory markers, increase neuronal growth factors (ngf) Indirectly: mood (decrease stress), increased attention, improves sleep. Increased levels with exercise= plays an essential role in neurogenesis and memory improvement= increased cognition. Produced by the liver and released to mediate growth hormone (increase gh= increased igf-1) Tested in blood, bone, or tissue, or brain. Associated with obesity, cvd, and cancer has a positive effect in some cases and a negative effect in other cases. 1: proteins that are released into bloodstream during in ammation, produced by white blood cells, measured via crp (a marker protein, high levels of in ammatory markers= greater risk of cognitive decline because of. Less likely to be elevated during/following exercise neurodegeneration (via plaques and tangles: crp.
