Kinesiology 2230A/B Lecture Notes - Lecture 7: Adipose Tissue, Glycerol, Transferase
19 Jan 2016
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Effects of altitude-importance of fitness and pace (work output) Altitude: ~3 degrees celsius / 1000 ft. Stimulus: catecholamines epinephrine and nor epinephrine. Removal of 2-carbon units by oxidation at the fatty acyl-coa. Each round of b-oxidation produces one mole of nadh, one molecule mole of fadh2 and one mole of acetyl-coa. If producing fatty acid, (15 minutes into low intensity exercise), Get accumulating of acetyl-coa, we will end up with more citrate. If inhibit pfk, the reaction slows and this means that upstream, glucose 6 phosphate is going to accumulate, this inhibits the breakdown of glucose in presence of hexokinase therefore slowing cho use from cho. We have limited cho stores and we can conserve the glycogen by using the fatty acid stores. When glucose/glycogen depleted = fatigued, cannot run on just fats. As exercise intensity gradually increases, increased hormonal stimulation activates ffa (and cho) use.
