Kinesiology 2230A/B Lecture Notes - Lecture 4: Anaerobic Glycolysis, Glut4, Blood Sugar

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Last day: during recovery atp is formed again, creatine and phosphate is going to be bound again, this happens from aerobic metabolism. The glycolytic system carbohydrates: glycolysis: the breakdown of glucose to pyruvic acid. (pyruvate) loss of hydrogen, glycogenolysis: the breakdown of glycogen to glucose. Glucose is super concentrated in the blood, fasted glucose concentration is 4-6mmols per liter: pancreas, beta cells create insulin to reduce blood glucose concentration (after eating a chocolate bar. Lactate dehydrogenase breaks down pyruvate to lactate: the only thing separating lactate and pyruvate is 2 hydrogens. If we don"t have hydrogens we can"t from lactate: nadh regeneration (reduction, nad is a co-factor which can accept hydrogens. It can be regenerated (oxidation - loss of h) in 2 ways: via lactate dehydrogenase, via shuttle systems connecting to the mitochondria. In the heart the electron acceptors are nad (more energy here)

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