Kinesiology 2230A/B Lecture Notes - Lecture 8: Citric Acid Cycle, Metabolic Pathway, Carbamino

• School: Western University
• Department: Kinesiology
• Course: Kinesiology 2230A/B
• Professor: Glen Belfry

Document Summary

Average female 12-16 g hb/100 ml blood: overlap between males and females, hb much higher in males, 13% difference between gender, oxygen carrying capacity differs as well. Saturation of hb with oxygen dependent on partial pressure of o2. Pp behaves differently in myoglobin vs. hb. Key point: for myoglobin to become saturated with o2 it has to have stronger affinity for o2 at any given partial pressure. Offload more than 90% of hb @ muscle. Need affinity of mg to be high so o2 at muscle so that o2 will bind: at any given pp have stronger affinity of mg to o2 compared to hb. Still offloaded about 50% of myoglobin to be used for etc. Little oxygen dissolved, has to be carried by hemoglobin. Effects on o2 saturation with hb important. Increase in h+ concentration causing drop in ph (more acidic) Increase in co2 levels (weak acid increase volume of co2 in blood, ph drops.