Kinesiology 2230A/B Lecture Notes - Lecture 5: Acetyl-Coa, Pyruvate Dehydrogenase Complex, Citrate Synthase

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Aerobic metabolism oxidative phosphorylation: adp + pi + o2 atp, fat can be used aerobically, not anaerobically, cho can be used both aerobically and anaerobically, e! production occurs in mito. Electron transport chain: nadh+h & fadh2 accumulate causes gradient moves h"s through etc releasing e! E! used to bind adp + p atp. Glucose: 2-3 atp / glucose-glycogen from glycolysis, 3-5 atp / glucose 2 nadh+h, 20 atp / 8 nadh+h from krebs (8 x 2. 5, 3 atp / 2 fadh2 (2 x 1. 5, total = 30-33 atp / glucose. 30-33 atp: coming from glucose or glycogen, skeletal muscle or heart tissue? (different shuttle systems) Fat mobilization from adipose tissue: stimulus epinephrine & norepinephrine. B-oxidation: removal of 2 cs by oxidation at the fatty acyl-coa, each round of b-oxidation produces, 1 nadh, 1 fadh2, 1 acetyl coa. Cleaves off two c"s in one path from the associated h"s each time.

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