Geography 2152F/G Lecture Notes - Lecture 2: Glucuronide, Symporter, Ileum

• School: Western University
• Department: Geography
• Course: Geography 2152F/G
• Professor: Mark Moscicki

Document Summary

Ficks law describes rate of transport as a function of different parameters such as concentration gradient across cell, surface area of membrane, and physiochemical properties of drug. If you want drug to be distributed through passive diffusion; you want drugs to be a good size (molecular weight < 500 da), good lipophilicity, and a lack of charge so that diffusion across biological membranes is favoured. Fluorine is added to drugs to increase lipophilicity (