Biology 1290B Lecture Notes - Lecture 1: Acinetobacter, Benzoyl Group, Micrococcus
Document Summary
Contact diseases can be caused by indigenous bacterial species. Skin protects underlying tissues from microbial colonization. Skin is protected by keratin, cells sloughing off in the epidermis, dendritic cells, sweet and sebum. Mucous membranes- line the inner surface of the body (internal skin), moist, releases mucous to protect against microbes, iga can intercept specific microbial invaders and defend against them. Moist areas of the skin will naturally harbour more bacteria and fungi. The majority of the organisms isolated from normal human skin are gram positive bacteria. Skin acts as a specific and non-specific site for defense against infection. Sebaceous: forehead and back, proprionibacterium acnes in hair follicles. Moist sites: navel, groin, foot have corynecbacterium. Dry sites: most diverse with staphylococccus acinetobacter and micrococcus. Acne is the most common skin condition in the developed world. 85% of adolescents and young adults develop acne. Progressions of acne: open comedones are blackheads, closed comedones are pimples.