Biology 1202B Lecture Notes - Lecture 22: Antimicrobial Peptides, Mast Cell, Endothelium
14 Jul 2016
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Milkmaids were generally immune to smallpox if they previously had cowpox. Inoculated an 8 years old boy with cowpox. Technique of infecting with a similar but less severe form of pathogen. Three lines of defense: first line barriers. Digestive enzymes: second line innate (nonspecific) A series of generalized internal chemical, physical, and cellular reactions that attack pathogens that have breached the first line. Relies on germ-line-encoded receptors that recognize a set of highly conserved molecular patterns that are present on the surface of pathogens but not found on host cells. Targets any invading pathogen and has no memory of prior exposure to that specific pathogen. Immunity requires an organism to differentiate between self and foreign. Molecules on the outside of the pathogen (i. e. , protein coat of virus) Plants 2 branches of immune system: a system that uses transmembrane prrs that respond to the.
