Biology 1202B Lecture 11: Lecture 11 .docx

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1952 hershey & chase: studied e. coli, the genetic material of the phage (viruses that infect bacteria) was dna not protein. The isotope used to label proteins was found in phage coats after infection but was not found in the infected cell or in progeny phages. Therefore, protein is not the genetic material: established the term transformation the conversion of a cell"s hereditary type by the uptake of dna released by the breakdown of another cell. 1953 watson, crick & franklin: used an x-ray diffraction model to study the structure of dna. The dna molecules within the fibre were cylindrical (about 2nm in diameter) Major patterns of atoms repeated at intervals of 0. 34 nm and 3. 4 nm within the. Distance between each pair of bases = 0. 34 nm. Each full twist of the dna double helix = 3. 4 nm: dna structure is a double helix.

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