Biology 1201A Lecture Notes - Lecture 10: Meiosis, Gamete, Quantitative Trait Locus
10 Dec 2015
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Document Summary
Characteristics of mendel"s work that set him apart as a genetic researcher. Unlike others mendel"s used a quantitative approach to study the science of inheritance. His techniques were especially rigorous and involved the use of statistical analysis in an era when qualitative, purely descriptive science was the accepted practice. He knew nothing about mutation, meiosis, cells/nuclei . He came up with fundamental model of inheritance . Careful experimentation with controlled crosses and quantitative analyses Variation in traits due to different alleles. The principle of segregation (first law): the two members of a gene pair (alleles) segregate (separate) from each other in the formation of gametes. Half the gametes carry one allele, and the other half carry the other allele. The principle of independent assortment (second law): genes for different traits assort independently of one another in the formation of gametes. In practice, the manifestation of mendel"s laws is seen by characteristic ratios of phenotypic classes, such as 3:1 and 9:3:3:1.
