Biology 1201A Lecture Notes - Lecture 13: Heterozygote Advantage, Founder Effect, Genetic Variability

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Processes that reduce, remove, or maintain heritable variation in populations. Reduce variation genetic drift (bottleneck and founder effect) Natural selection (depends what it selects for) Effect of non-random mating (e. g. , inbreeding) on allele frequencies and on genotype frequencies. Non-random mating decreases the gene pool of a population. When a particular phenotype is preferred (height, fur colour), mating does not occur randomly, and thus, it will not satisfy the hardy equilibrium. This decreases heterozygous offspring while increasing homozygous offspring. Because relatives often carry the same alleles, inbreeding generally increases the frequency of homozygous genotypes and decreases the frequency of heterozygotes. Inbreeding will cause more homozygous recessive genotypic frequencies. Increase or decrease in genetic variability just means that the gene pool is getting larger or smaller, that"s why non-random mating decreases the gene pool of a population. Genetic variability can lead to evolution, but they are not directly related.

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