Biology 1201A Lecture Notes - Lecture 3: Snrnp, Microrna, Spliceosome
2 Oct 2016
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Document Summary
Rna polymerase to transcribe mrna from the dna template: activators (another type of dna binding protein) Post- transcriptional regulation (regulation after dna becomes rna; occurs in eukaryotes: dna gets transcribed base-for-base into pre-mrna. Then this pre-mrna strand needs to be modified before it leaves the nucleus as fully processed mrna. Processing helps stabilize / protect the mrna: only exons make it into finished mrna. Multiple adenosine monophosphates (basically adenine bases) are added to act as a buffer for exonucleases. The poly-a tail is built until it"s about 250 nucleotides long: rna editing - results in sequence variation in mrna molecule. Non-coding rna (crna: ncrna is a functional rna molecule that is not translated into a protein. Also relevant during translation: small nuclear rna (snrna) - avg. length is ~150 nucleotides. Primary function is in processing of pre-mrna in the nucleus. They also aid in regulation of transcription factors or.
