Biology 1002B Lecture Notes - Lecture 5: Peripheral Membrane Protein, Alpha Helix, Olive Oil
12 Mar 2016
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Have unique features: peripheral membrane proteins sit on the surface. 2nd law tells you that this is the case and nothing stays around for ever: the unsaturated fats are replaced by fully saturated fats if you shift back to warm temperature. Don"t tend to find a lot of charged amino acids in these alpha helices". Alpha helical secondary structure minimizes the charges. Protons, oxygen, nitrogen are interacting with hydrogen bonding. Alpha helices, kinda: the orange part would have classic amino acids. You can see 7 distinct region in rhodopsin where the polarity average of 3 is low (hydrophobicity index is high) The hydropathy index is higher if the region is made up of non polar amino acids. You don"t need the tertiary structure to determine this. Membrane transport: diffusion: oxygen, carbon dioxide simply diffuse through the membrane, driven by entropy: energy spreading, the driving force, facilitated diffusion: for bigger molecule, diffusion down a concentration gradient.
