Biology 1002B Lecture Notes - Lecture 10: Neanderthal Genome Project, Nucleic Acid Double Helix, Polynucleotide
28 Feb 2016
School
Department
Course
Professor
Document Summary
Material covered dna as hereditary material, dna structure, Catalogued sites where all (or nearly all) present day humans have the same snp but differ from neanderthal. Differ at 31, 389 snps 87 proteins. Early 1900s, scientists thought were the molecule of heredity. 20 amino acids vs 4 nucleotides protein contains more information per unit. Took a lot of convincing that heredity molecule was dna . Despite result of avery and griffith, not all were convinced. Proteins made more sense contained more information (20aa compared to 4 nucleotides) Results (finally) proved dna is the genetic material. Complimentary base pairing: a-t (2 hydrogen bonds, c-g (3 hydrogen bonds) Incorporated into dna: coli grown on medium with n915) Pcr allowed for the study of ancient dna. Many studies isolated dna from amber encased organisms. Bone fragments from a coal mine in utah. Isolated dna, pcr amplified region of mitochondrial cytochrome b, sequenced dna. Determined that sequence was different from other sequences the database.
