Biology 1002B Lecture Notes - Fall 2018 Lecture 20 - Lac operon, Bioluminescence, Viral vector
Document Summary
Normal cell division results from the balanced expression of proto-oncogenes (stimulate cell division) and tumour suppressor genes (which restrict cell division). Few viruses actually get into the genome, hpv does not. Virus might down regulate tumour suppressor genes (like p53) Virus might disturb the network of gene products such that a cell can fall into a cancer fate. Virus might bring its own cdk that stimulates the cell to divide. Optogenetics provides control of speci c neurons at speci c times in behaving animals. Action potentials are propagated by movement of ions across membranes as a wave of depolarization (positive charge ooding into cells). Action potentials can be controlled by channelrhodopsin from chlamydomonas because the channels open when exposed to blue light. Chlamydomonas nuclear genome can be chopped with restriction endonucleases and you can create a recombinant dna molecule that contains the chlamydomonas channelrhodopsin gene.
