Biology 1001A Lecture Notes - Lecture 6: Okazaki Fragments, Nucleic Acid Double Helix, Alpha Helix
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28 Mar 2016
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Independent study outcomes: purine and pyrimidine base-pairing in dna/rna. Pair by complementary base pairing: a-t, c-g. Semi-conservative: in dna replication, a double stranded dna splits into two single strands that are templates for the synthesis of a new strand, then becoming double stranded dna (from one we make two) Semi-discontinuous: also known as discontinuous replication, is the replication in which a dna strand is formed in short lengths that are synthesized in the direction opposite of dna unwinding: these short lengths are called okazaki fragments. Leading strand: dna strand synthesized in the direction of dna unwinding (at origin) Lagging strand: dna synthesized discontinuously in opposite direction of dna unwinding: general action of proteins in fig. Single stranded binding proteins (ssb"s): stabilize single stranded dna and prevent the two strands at the replication fork from reforming double stranded dna: topoisomerase: avoids twisting of dna ahead of replication fork by cutting the dna, turning the.
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