Biology 1001A Lecture Notes - Lecture 18: Genotype Frequency, Allele Frequency, Gene Pool

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Biology lecture 13 outcomes: hardy-weinburg, selection, and fitness. Pre-lecture: meaning of gene pool, allele frequency, genotype frequency, gene pool: sum of all alleles at all gene loci in all individuals, allele frequency: relative abundances of different alleles at each gene locus. A particular allele will increase in frequency in the next generation if individuals carrying that allele leave more offspring than individuals carrying other alleles: absolute fitness: number of surviving offspring produced over an individual"s lifetime. Influenced by survival to adulthood, longevity, attracting mates, fertility, and offspring survival: must standardize absolute fitness to get relative fitness, the fittest genotype in the population has w=1, all other genotypes in population. The strength of selection is dependent on the relative fitness (w) In diploid organisms dominance relationships can interact with selection. Selection for the dominant allele can quickly operate. Selection against the dominant allele can weed out all the copies because selection is able to see all these copies.

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