Biology 1001A Lecture Notes - Lecture 12: Heterozygote Advantage, Genotype Frequency, Allele Frequency
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Meanings of gene pool, genotype frequencies, allele frequencies, genetic equilibrium. Gene pool the sum of all alleles at all gene loci in all the individuals of a population. Genotype frequencies the percentages of individuals possessing each genotype. Allele frequencies the relative abundances of different alleles. Genetic equilibrium the point at which neither allele frequencies or genotype frequencies change. How to calculate allele frequencies, given observed genotype frequencies. Determine the total number of alleles by multiplying the total number of individuals by the number of alleles. Find how many of each allele are contributed by each individual and multiply this by the number of individuals of each genotype to determine how many of each allele are present in total. Homozygote individual = 2 dominant or 2 recessive alleles. Heterozygote individual = 1 dominant allele, 1 recessive allele. Divide the number of each allele by the total number of alleles to find the allele frequency.