Biology 1001A Lecture Notes - Lecture 7: Human Genome Project, Photolyase, Covalent Bond
23 Jun 2019
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List of mechanisms to ensure inheritance of sameness. Telomerase to make sure your chromosomes don"t shorten. Dna polymerase can only add to a properly paired 3" base. Bases of dna is methylated, following replication the new strand is not methylated yet, therefore the strands can be differentiated. Photons of uv light have the right amount of energy to be absorbed by purines especially thymine"s and become covalently linked together. Photolyase can break the covalent bond the thymine has formed. Maybe at one point our ancestors were nocturnal. Double stranded break, through non-homologous end joining can join the strands together, though is sloppy and some sequence can be lost. Simple less complex cells have less dna than complex organisms. Most of the genome is housekeeping keeps you alive. There is no such thing as one sequence of the human genome. Human genome project was just the sample of the human genome. Everyone has a different variation of the genome.
