Biology 1001A Lecture Notes - Lecture 13: Heterozygote Advantage, Genetic Drift, Allele Frequency

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Selection, genetic drift and other forces that take a population out of hardy weinberg. Selection: occurs if some genotypes have higher absolute fitness- higher reproductive success over a lifetime, not all genotypes have different fitness, selection can result in allele frequencies changing- evolution. Agents of microevolutionary change: mutation, heritable change in dna. If mating is not random with respect to genotype: assortative- like mates with like, ex. Geese has colour polymorphism- grey and white: prefer to mate with geese of same colour as themselves, disassortative- mates with opposite. Inbreeding- incest (mating with close relatives: similar genome. Assortative- individuals choose mates based on similarity at one particular locus: for a certain trait, and all genotypes have the same fitness, p: 250aa, 500aa, 250aa. Bio lecture 13- nov 1 2016: f1: 375aa, 250aa, 375aa, no longer in equilibrium, allele frequencies have not changed because there was no selection, does not cause evolution.

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