Biology 1001A Lecture Notes - Lecture 5: Replisome, Dna Replication, Sister Chromatids
9 Oct 2016
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It has proceeded beyond the mitosis checkpoint false, the mitosis checkpoint is between metaphase and anaphase, it will not let the sister chromatids pull apart until they are lined up. It contains some circular chromosomes true, the chromosomes contains that of mitochondria and chloroplasts, which both have circular dna. It has 2c the amount of dna false, metaphase has 4c. It has tubulin polymers true, there are spindle microtubules. Double helical structure of dna with two antiparallel backbones. Distinct 3" and 5" end confers polarity on dna backbones. Daughter strands contain one new backbone and one old backbone. Dna polymerase adds to a free 3" end. Every dna/rna polymerase adds nucleotides to the 3" oh. Dna is read in the 3" to 5" direction. Dna is replicated (nucleotides added) in the 5" to 3" direction. The original helix is antiparallel the polymerase must read dna strands 3" to 5".
