Biology 1001A Lecture Notes - Lecture 8: Caesium, Dna Replication, Iodine
5 Oct 2016
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Draw out how replication errors give rise to snps. Thymine is just uracil with a methyl group. Dna polymerase cannot distinguish thymine from 5- Replication slippage: can happen in the template or in the new strand. On new strand: adds in an extra base pair addition. On old strand: ends up losing a base pair deletion. Dna replication is a mechanism of generating diversity/variation. When intense radiation passes through water (in our bodies), electrons are stripped away, which results in the destruction of chromosomes. Decay of radioactive iodine and cesium creates ionizing radiation . Iodine has a relatively short half-life (1-week); cesium has a relatively long half- life (30-years) Translocation: where segments of different chromosomes have exchanged places not. Unequal recombination can generate copy number variations (cnv) Normal crossing-over: recombination attaches a piece of the red chromosome to the blue chromosome not translocation, just swapping the versions results in recombinant chromosomes that have the same # of genes.
