Biology 3466B Lecture Notes - Lecture 2: Allele Frequency, Zygosity
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Aa p mq f+p fq m q mq f aa. At generation f1 the hw equilibrium was reached. The bigger the differences in allele frequencies between the sexes are, there will be more heterozygotes in f1. When the two p values differ by one, for example, pf=1 and pm=0, there will be no homozygotes in f1 because one copy of allele is required from each parent, pf pm=0 and qf qm=0. All offspring will be heterozygotes - pf qm=1. Therefore, when the differences in allele frequencies between the sexes are big, there will be more heterozygotes in f1. The genotype variance maximum occurs when p=0. 5 because all three genotypes are present within the population, and each genotype males up a significant proportion. The numbers of aa genotypes and aa genotypes are equal when p is around 0. 667, or as a fraction, 2/3. 0. 00 s e i c n e u q e r.