Biology 3338A Lecture Notes - Cranial Nerves, Aorta, Cell Potency

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4: trunk nc migrate through 2 paths ventral; dorsal lateral, dl pass through epi and dermyatome; mgrate just beneath epidermis (btw epi and dermya, v migrate thtrougth the somite; through ant half of sclerotome. Nc has half eph repel: dl migration is everywehere not restricted, v path is restericeted by semaphroin and ephrins; nc have receptors that, need chemotaxis attraction. Don"t fully understand really what this attraction thing is. 6: if inhibit nrp1 receptor, cells start to migrate around scleratone; don"t react to semiphorin, wont differentaite properly, not only nc thsta migrate though somite; a lot of axons (symp neurons) Receive info that tells them whre they go relative to the body plan. 10: cranial nc cells to form bone need bmp. 11: cranial nc give rise to many different structures, cardiac nc give rise to part of aorta also, leads to aortic arches, fgf8 attract cardiac nc cells in phar ecto.

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