Biology 2581B Lecture Notes - Lecture 21: Homologous Chromosome, Patau Syndrome, Edwards Syndrome

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Lecture 21: transposable elements and variations in chromosome numbers. First evidence by marcus roades in 1930s and described in detail by barbara mcclintock in maize from 1940 onwards: earlier evidence by marcus. But they exist in many organism including mammals, insects, plants : do not just exist in maize, come in different shapes, sizes, colors etc, find it in any type of organism. Transpose via reverse transcription of an rna intermediate. Use rna intermediate in order to jump from one location to another within the genome: 2. Transpose directly from dna to dna and do not have rna intermediate. Many different types: some with cool names: mariner, gypsy, looper, springer, hopper, stalker, invader, diver, frogger, all refer to different types of transposable elements, all have something to do with moving. Can be 50 bp to 10 kb in length: can be small or big depending on what kind you are talking about.

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