Biology 2581B Lecture Notes - Lecture 17: Point Mutation, Ultraviolet, Intron

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Differences in sizes of genomes or chromosomes. Stretches that are rich in certain nucleotides, at or cg. If yes, how many, is it tightly packed, or are there long stretches of non coding dna between coding information. What is in that non coding dna: regulatory elements, repeats, mobile elements, foreign dna, pseudo genes. Are the genes uninterrupted stretch of coding information or bombarded with non coding introns. What is happening to the rna after: processed, translated with a non standard code? modifications. Looked at different genome architecture: organelles, nuclei, etc. from different species. When thinking about genome architecture, have to look at everything size, structure, content : euglena ribosomal rna in nuclear system, trypanosome weird mitochondrial dna with circles, unconventional gene expression in. There is huge diversity in genome architecture diversity can be observed. Variation not only on a genomic level and the way information is expressed nuclear compartment with polycistronic transcripts. Observed: within cells, within lineages, between different lineages.

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