Biology 2581B Lecture Notes - Lecture 6: Human Genome, Alphaproteobacteria, Plasmodium
27 Jan 2017
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Genomes are made of one or more chromosomes. Chromosomes are messy, full of proteins, big bundles. Don"t confused ploidy ( copies ) with the number of chromosomes. Genome size: is the length of 1 complete copy. Both are double stranded (except for some viruses) Genomes can also be a mixture of linear and circular genomes in a single genetic environment (diverse) Linked together repeats of the entire genome. Big deal for genome sequencing because you would think that the genome is circular when in reality it is just a linear repeat. Sequencing and assembly made it look like a circle but it is not. Not sequenced or included in the genome (size) Hundreds of thousands of copies per cell. 760 gb of dna in a cell! Links to hypothesis: genome size/ amount is related to cell size. One of the only bacteria with a linear genome. Plasmids can be both linear and circular.
