Biology 2382B Lecture Notes - Lecture 4: Translocon, Microsome, Secretion

• School: Western University
• Department: Biology
• Course: Biology 2382B
• Professor: Robert Cumming

Document Summary

Newly made peptides must be directed to the correct destination. Targeting: targeting occur while the protein is being made or after it is made, direct proteins to the right destinations (organelles, during or after synthesis, achieved frequently by certain signals like the address. It recognizes the signal and it goes to the destination. Have a targeting signal certain sequence of amino acids somewhere usually directing it towards an organelle. During or after synthesis: can target proteins to certain organelles, like a mailing system put an address on and the mail man knows to deliver it to that address. Involves proteins that have certain signal sequence that will help facilitate the movement of the protein to the right destination. Involved with a signal sequence which tells the cell to take the protein and take it. Sorting: direct proteins to the secretory pathway (er, golgi, lysosomes) Modification allows sorting to whether they are secreted, captured with lysosomes,