Biochemistry 2280A Lecture Notes - Lecture 13: Allosteric Regulation
18 Dec 2015
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Biochem lecture 13- metabolism and enzyme regulation: basic concepts. Explain what a metabolism pathway is, what flux is, and the difference. Based on deltag, predict whether a reaction in a pathway is likely to be. Compare and contrast regulation of enzymes in metabolism pathways between catabolism and anabolism regulated by allostery and by covalent modification of proteins energy during the process. Catabolism breaking larger molecules into smaller ones; extracting. Processes are oxidative getting reducing powers out. Anabolism building things up, uses energy and reducing powers ( a source of electrons) Pathways cell acts one thing to make something else, that acts on something else reactions are stung together to end up with an ultimate pattern negative. Flux = rate of conversation of a to e (first molecule to the last) Conversation is efficient when net deltag for whole pathways is. Will not see a reaction with a positive deltag in the direction you want to go.
