Biochemistry 2280A Lecture Notes - Lecture 2: Methylene Group, Tyrosine, Amine
1 Nov 2018
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Document Summary
Each group of 3 nucleotides is called codon: each codon specifies one amino acid, according to trna, it will be charged by different proteins, as the machinery in ribozymes comes along and reads the mrna. Different trna bounds with unique amino acid, bound onto rna. Serine is polar group: oxygen has negative character, while hydrogen has positive character, they can lose a proton and get a negative charge, e. g. 100% protonated carboxyl group, and 100% protonated amino group. When the ph is raised, we first consider the carboxyl group of 2. At ph 2, we lost 50% of the carboxyl group. Further ph (e. g ph 7), we lost pretty all protons of the carboxyl group. But the protons is still on the amino group. At ph 10, the net charge of amino group is +0. 5 because we lost 50% the protons: net charge of amino acids.
