Biochemistry 2280A Lecture Notes - Lecture 17: Atp Synthase, Atp Hydrolysis, Electrochemical Gradient

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12 Dec 2016

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Topic 14 continued: q: two different electron carriers (ubiquinone and cytochrome c) are used to move electrons between complexes of the electron transport chain. You don"t want to use the same carrier because of the electrons going from low affinity carriers to high affinity carriers. If you replace cytochrome c with ubiquinone, it would be like going backwards because they have different affinities for electrons. C. i don"t know: complex ii: succinate dehydrogenase. This is where the electrons from fadh2 go. Is an enzyme in the citric acid cycle in the inner mitochondrial membrane. Accepts 2 electrons from succinate transfers to fad to make fadh2. Electrons go from fadh2 iron sulfur centre coenzyme q. No protons are pumped across the membrane when this reaction occurs. Basic job is just to move the electrons. In a way, it"s inefficient because we"re not harnessing any energy: electron transfer within complex ii. Fad/fadh2 is covalently bonded to complex ii.

Related Questions

19. Which of the following is a component of Succinate dehydrogenase in Electron transport chain?

A. Niacin

B. FMN

C. FAD

D. Coenzyme Q

E. Lipoic acid

20. In electron transport the flow of electrons:

A. is bidirectional

B. goes from a high energy state to a low energy state

C. takes place in the outer mitochondrial membrane

D. are used to pump H+ into the mitochondrial matrix

21. Which of the following statements about the electron transport chain is NOT correct

A. It is located in the inner mitochondrion membrane

B. Cytochrome c accepts electrons from complex II

C. Cytochrome c oxidase (complex IV) accepts electrons from Cytochrome c

D. Complex I is called NADH dehydrogenase

E. Coenzyme Q accepts electrons from complex I and complex II

22. In the electron transport chain, the enzyme cytochrome C oxidase:

A. Uses H2O as a substrate

B. Produces HOOH as a product

C. Cannot function if oxygen is absent

D. Accepts electrons from hydrogen ions

E. Uses ADP and Pi as substrates

5. Almost all of the oxygen (O2) one consumes in breathing is converted to: a. acetyl-CoA. b. carbon dioxide (CO2). c. carbon monoxide and then to carbon dioxide. d. none of the above. e. water.

6. A new compound isolated from mitochondria is claimed to represent a previously unrecognized carrier in the electron transfer chain. It is given the name coenzyme Z. Which line of evidence do you feel is the least conclusive in assigning this compound a position in the electron transfer chain? a. Alternate oxidation and reduction of the mitochondrion-bound coenzyme Z can be readily demonstrated. b. Removal of coenzyme Z from the mitochondria results in a decreased rate of oxygen consumption. c. The rate of oxidation and reduction of mitochondrion-bound coenzyme is of the same order of magnitude as the overall rate of electron transfer in mitochondria as measured by oxygen consumption. d. The reduction potential of Z is between that of two compounds known to participate in the electron transport chain e. When added to a mitochondrial suspension, coenzyme Z is taken up very rapidly and specifically by the mitochondria.

7. Which of the following is not true of the citric acid cycle? a. All enzymes of the cycle are located in the cytoplasm, except succinate dehydrogenase, which is bound to the inner mitochondrial membrane. b. In the presence of malonate, one would expect succinate to accumulate. c. Oxaloacetate is used as a substrate but is not consumed in the cycle. d. Succinate dehydrogenase channels electrons directly into the electron transfer chain. e. The condensing enzyme is subject to allosteric regulation by ATP and NADH.

8. Conversion of 1 mol of acetyl-CoA to 2 mol of CO2 and CoA via the citric acid cycle results in the net production of: a. 1 mol of citrate. b. 1 mol of FADH2. c. 1 mol of NADH. d. 1 mol of oxaloacetate. e. 7 mol of ATP.

Biochemistry 2280A Lecture Notes - Lecture 17: Atp Synthase, Atp Hydrolysis, Electrochemical Gradient

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