Anatomy and Cell Biology 4451F/G Lecture Notes - Lecture 23: Cochlear Nerve, Oxidative Stress, Afferent Nerve Fiber
7 Dec 2017
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Outline the key structures in peripheral and central auditory systems. Describe hair cell transduction and cochlear mechanics. Explain sensorineutral hearing loss associated with genetic forms, as well as aging and noise exposure. Describe how the auditory cortex adapts to hearing loss (ex tonotopic and crossmodal reorganization) Summarize the potential therapies for hearing loss, with emphasis on how they target the various mechanisms of sensorineural hearing loss. 3 functional divisions of ear (outer, middle, inner) Funnel sounds of our outer environment towards eardrum: pinna = outer cartilaginous structure, external auditory meatus = ear canal tymphanic membrane = eardrum. Middle: eardrum moves these 3 bones ossicular chain, amplify sounds, to move fluid in cochlea. Inner: cochlea is here, pressure waves from bones moving get converted to electrical signals. If you unroll cochlea and take section of it youll see organ of corti. 1 row = 4000, 3 rows = 3x4000 inner hair cells have afferent axons this is how hearing originates.
