Anatomy and Cell Biology 3309 Lecture 3:

• School: Western University
• Department: Anatomy and Cell Biology
• Course: Anatomy and Cell Biology 3309
• Professor: Martin Sandig

Document Summary

Acb 3309 lecture 3 (the structural basis of cell bio) The cell part 2 cytoskeleton, nucleus, & nucleolus. Made up of: microtubules, actin filaments, and intermediate filaments. 24nm hollow cylinders largest component of cytoskeleton. Come together at a center point and fan out like sun rays. Consists of and tubulin proteins form a dimer: have associated proteins called maps, dimers stack up and arrange themselves circumferentially (like twizzler or barbershop barrel, dimers self-assemble. Tubulin rings in the mtoc serve as a starting point for mt growth: base/structural support of the mt, 1 or 2 layers of it. Polarity (+) (growing) end: where dimers are stacking on top of each other (-) (nongrowing) end, associated with -tubulin. Mts aren"t static structures once they"re formed revision/growth at the (+) end. Form centrioles, involved in the mitotic spindle: cell movement and movement of extracellular fluid. Form basal bodies, axonemes of cilia and flagella (see cell junctions and cell surface modifications lecture next week)