Anatomy and Cell Biology 3309 Lecture 6: ANATCELL 3309 Lecture 6 Dense Connective Tissue

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Most of these tissues are derived from mesenchymal stem cells. These are the cells that will give rise to these tissues. Mechanically loaded tissues and contain mainly type 1 collagen. And the cells are very highly oriented in these tissues. If you look at them in histological section the nuclei of the cells is the most prominent thing you can see. Don"t really see the cytoplasm mechanical load. The nuclei are very elongated in one direction due to the application of. In these tissues by default contain a lot of chrondroitin sulfate gags. The collagen content is very high, it makes up a majority of the tissue. There is a lot of ground substance. A lot of waters in these tissues as well. Mostly type i collagen, also elastic and type iii collagen fibers. Collagen fibers in parallel bundles with cells along longitudinal axis. Non-fiber components decorin, chondroitin sulfate, versican, aggrecan. When you tear a ligament have tendency to scar.

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