Anatomy and Cell Biology 3309 Lecture Notes - Lecture 10: Great Saphenous Vein, Venae Cavae, Capillary

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Thicker walls compared to the lumen than can be seen in venous system. At all times blood is exposed to endothelial cells that are anti-thrombogenic. The spleen is an exception, rbc leave the blood circulation. Blood vessels are designed fro the exchange of nutrients, gases. Degree to which endothelial cells allow exchange to occur depends on what tissue you are looking at. In the liver they are very leaky, brain is opposite. Capillaries will allow plasma to leak into connective tissue, the lymphatic system collects this tissue fluid and returns it to the circulation. If we consider pressures the lymphatic system will be at a much lower pressure. It has to be low because it has to be able to go from the connective tissue to lymphatic vessels by passive diffusion, if it goes against a gradient or pressure it will not work. What happe(cid:374)s if (cid:455)ou"re l(cid:455)(cid:373)phatic s(cid:455)ste(cid:373) is (cid:374)ot fu(cid:374)ctio(cid:374)i(cid:374)g (cid:455)ou get ede(cid:373)a.

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