BIOL 2131 Lecture Notes - Lecture 6: Tata Box, Wild Type, Noncoding Dna

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Chapter 2: genes code for rna and proteins. Once the human genome was sequences, want to know what it means. Different chromosomes were given to different labs: it was so hard to stitch it all together. If you have a bunch of dna, you look for specific landmark sequences that potentially identify where a particular gene is: tata box- identifies a promoter. All genes have a particular sequence that controls the activation of that gene in terms of gene expression (transcription) In eukaryotic genes, the vast majority of genes have a tata box: appears just prior to where transcription occurs in a gene. But what does the gene encode: protein or rna only, look for specific codon/amino acid reading frame sequences, start codon, stop codon. All genes that encode proteins have codons: 3 base pair letters that correspond to specific amino acids from the rna. Tata does not mean it is a promoter: it does occur randomly every so often.

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