BIOL 312 Lecture Notes - Lecture 30: Murine Typhus, Scrub Typhus, Chikungunya

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Opossum efficiently removes ticks and the few that remain feed and grow slowly. Tick and lyme densities are much greater in white-footed mice: conservation and biodiversity implications. Arthropod vectored bacterial disease: fleas: plague, murine typhus. Plague: vectored by fleas, caused by yersinia pestis. Among worst epidemics in history killed 100 million people in 6th century (1/4 pop in 14th century), less common after 1700s. Infection of the lymphatic system (bubo swollen gland transmitted by fleas only), infection of lungs results in pneumatic form (highly infectious and deadly). Forms a plug in the flea gut, flea regurgitates infected blood into host wound as it tries to feed (other modes of environmental transmission as well). Insect-vectored viruses: arboviruses (= arthropod borne viruses): replicate inside vector and vertebrate host. Encephalitis: caused by a collection of viral diseases in 3 families, each one using a preferred mosquito host, most infections are asymptomatic ____________ Zika virus: first described in 1947 in africa, reached the.

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