PSL300H1 Lecture Notes - Lecture 5: Muscle Contraction, Osteoclast, Thyroid
Document Summary
2:48 pm: why is calcium critical for normal physiology? o o o o o o. Building and maintaining bone: calcium homeostasis and distribution. Absorbed by small intestine and excreted in urine from kidneys o o o o o o. Peptide hormone that is released from pth is released from parathyroid gland o o o o that is on the side of your necks o. Calcium sensing receptors bind to ca, which is a g protein receptor, which. Pth secretion (synthesis) is inhibited o activates the regulatory pathway which shuts off pth release: when low levels of ca there is alot of binding to pth receptor thus more pth is released o o. High levels of calcium beyond that threshold inhibit or suppress pth. Low levels activate release of pth: pth increases plasma [ca] by acting directly on bone and kidney. Activate on number of target tissues because its a goal to increase ca.
