PSL300H1 Lecture Notes - Lecture 6: Meninges, Pia Mater, Dura Mater
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Also noticed the equal concentration of na+ in the blood and interstitial fluid whereas, the [k+] in the blood is about 2x the concentration in the interstitial fluid. There is also a higher [protein] in the interstitial fluid. There"s a lack of dopamine so we should inject dopamine! But dopamine doesn"t cross bbb so we need to inject a precursor for dopamine called l-dopa which can cross the bbb. Once l-dopa cross the bbb and gets into the brain, it can be converted into dopamine levitate symptoms. Bbb is purposely broken to allow release of hormones. In circumventricular organs (around 3rd ventricle) the bbb is broken so neurons can sense specific chemical concentration: generally, bbb is broken in areas that interact with the endocrine system or require sensitivity to metabolites in the plasma. Brain encasings: the brain and spinal cord also physically protected by the skull and the meninges, the skull is the strongest part of the body, meninges.
